Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lysSTIGRFAM: lysyl-tRNA synthetase; KEGG: sma:SAV_4749 lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (598 aa)    
Predicted Functional Partners:
lysS-2
TIGRFAM: lysyl-tRNA synthetase; KEGG: krh:KRH_21510 putative lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF472; protein of unknown function DUF471; protein of unknown function DUF470; nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family.
    
 0.918
Tpau_0570
KEGG: nfa:nfa4100 hypothetical protein.
       0.662
Tpau_0919
KEGG: cai:Caci_5177 hypothetical protein.
  
     0.517
Tpau_0572
Lsr2 protein; KEGG: msm:MSMEG_6092 Lsr2 protein.
       0.484
Tpau_3917
PFAM: protein of unknown function DUF990; KEGG: fal:FRAAL3907 putative ABC-type uncharacterized transport system, permease component.
  
     0.460
Tpau_1331
PFAM: membrane-flanked domain; KEGG: msm:MSMEG_0865 membrane flanked domain- containing protein.
  
     0.457
Tpau_3918
PFAM: protein of unknown function DUF990; KEGG: fal:FRAAL3906 putative integral membrane transport protein.
  
     0.435
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.434
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.416
Tpau_0566
PFAM: Domain of unknown function DUF2520; Putative oxidoreductase/dehydrogenase, Rossmann-like domain; KEGG: rop:ROP_43300 hypothetical protein.
       0.415
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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