Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_0587PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: mgi:Mflv_1435 alpha/beta hydrolase fold. (258 aa)    
Predicted Functional Partners:
Tpau_0588
PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: rer:RER_20980 DNA glycosylase.
       0.778
Tpau_1130
PFAM: alpha/beta hydrolase fold; KEGG: rop:ROP_64360 putative hydrolase.
  
     0.697
Tpau_0586
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: rha:RHA1_ro04436 hypothetical protein.
       0.686
Tpau_0589
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rsa:RSal33209_1125 short chain dehydrogenase.
  
  0.632
Tpau_0590
PFAM: regulatory protein TetR; KEGG: sco:SCO4008 TetR family regulatory protein.
       0.562
Tpau_4023
KEGG: fre:Franean1_1509 alpha/beta hydrolase fold.
  
     0.495
Tpau_0475
PFAM: alpha/beta hydrolase fold; KEGG: cmi:CMM_2872 putative hydrolase/acyltransferase.
  
     0.457
Tpau_1823
PFAM: alpha/beta hydrolase fold; KEGG: mav:MAV_3609 hydrolase.
  
     0.432
Tpau_0585
PFAM: protein of unknown function DUF308 membrane; KEGG: nfa:nfa31070 hypothetical protein.
       0.418
Tpau_2805
KEGG: rha:RHA1_ro01294 hypothetical protein.
  
    0.408
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.