Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (253 aa)    
Predicted Functional Partners:
Tpau_3520
Allophanate hydrolase subunit 2; KEGG: ach:Achl_0175 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1.
  
 0.992
Tpau_1594
Urea amidolyase related protein; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: urea amidolyase related protein; KEGG: msm:MSMEG_2187 UreA amidolyase; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1.
 
  
 0.957
Tpau_2546
TIGRFAM: gamma-glutamyltransferase; KEGG: rop:ROP_41600 putative gamma-glutamyl transpeptidase; PFAM: gamma-glutamyltranspeptidase.
     
  0.900
Tpau_3727
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
Tpau_0610
KEGG: nfa:nfa4440 putative ABC transporter ATP- binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.822
Tpau_0611
PFAM: periplasmic solute binding protein; KEGG: rop:ROP_44070 putative ABC transporter substrate-binding protein.
       0.819
Tpau_0609
PFAM: ABC-3 protein; KEGG: rop:ROP_44050 putative ABC transporter permease protein.
       0.811
Tpau_1497
KEGG: rop:ROP_08930 glutamine synthetase I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
   
 
  0.805
Tpau_1510
KEGG: mab:MAB_1933c glutamine synthetase, type I (GlnA1); TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
   
 
  0.805
Tpau_2888
KEGG: rha:RHA1_ro05312 glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region.
   
 
  0.805
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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