Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_0618KEGG: nca:Noca_1011 4-carboxymuconolactone decarboxylase; TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; alpha/beta hydrolase fold. (400 aa)    
Predicted Functional Partners:
Tpau_0617
PFAM: fumarate lyase; KEGG: art:Arth_4076 3-carboxy-cis,cis-muconate cycloisomerase.
 
 
 0.997
Tpau_0621
TIGRFAM: 3-oxoacid CoA-transferase, B subunit; KEGG: art:Arth_4071 butyryl-CoA:acetate CoA transferase; PFAM: coenzyme A transferase.
 
 
 0.985
Tpau_0620
TIGRFAM: 3-oxoacid CoA-transferase, A subunit; KEGG: ach:Achl_3848 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.
 
 
 0.984
Tpau_0615
KEGG: ach:Achl_3854 protocatechuate 3,4- dioxygenase, beta subunit; TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase.
 
  
 0.966
Tpau_0616
KEGG: art:Arth_4077 protocatechuate 3,4- dioxygenase, alpha subunit; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase.
 
  
 0.962
Tpau_4060
PFAM: Carboxymuconolactone decarboxylase; KEGG: mva:Mvan_4934 carboxymuconolactone decarboxylase.
 
  
0.922
Tpau_0206
PFAM: alpha/beta hydrolase fold; KEGG: mmi:MMAR_0086 hydrolase.
    
 0.902
Tpau_0619
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: aau:AAur_4039 beta-ketoadipyl-CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.798
Tpau_0622
Transcriptional regulator, IclR family; TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: Transcriptional regulator IclR; regulatory protein IclR; KEGG: ach:Achl_3846 transcriptional regulator, IclR family; SMART: regulatory protein IclR.
 
   
 0.774
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 0.675
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.