Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_0647Two component transcriptional regulator, LuxR family; KEGG: cms:CMS_1730 putative two component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR. (212 aa)    
Predicted Functional Partners:
Tpau_0648
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: cms:CMS_1731 putative two component sensor kinase.
 
 
 0.943
Tpau_0971
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: ami:Amir_0531 histidine kinase.
 
 
 0.835
Tpau_1990
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sco:SCO4362 two component system sensor kinase.
 
 
 0.832
Tpau_1008
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: ami:Amir_4000 histidine kinase.
 
 
 0.830
Tpau_2873
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: nfa:nfa42540 putative two-component system sensor kinase.
 
 
 0.825
Tpau_2413
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sma:SAV_1281 two-component system sensor kinase.
 
 
 0.806
Tpau_3508
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: rop:ROP_64560 putative two-component histidine kinase.
 
 
 0.765
Tpau_1411
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: rha:RHA1_ro05271 sensor kinase, two-component system.
 
 
 0.739
Tpau_1875
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: rer:RER_29170 two-component histidine kinase.
 
 
 0.728
Tpau_0645
PFAM: protein of unknown function DUF214; KEGG: lxx:Lxx14520 ABC transporter, permease protein.
     
 0.594
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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