Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_0649Methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (283 aa)    
Predicted Functional Partners:
Tpau_0650
KEGG: rha:RHA1_ro04522 TetR family transcriptional regulator.
 
     0.678
Tpau_0648
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: cms:CMS_1731 putative two component sensor kinase.
 
     0.649
Tpau_0645
PFAM: protein of unknown function DUF214; KEGG: lxx:Lxx14520 ABC transporter, permease protein.
 
     0.603
Tpau_0647
Two component transcriptional regulator, LuxR family; KEGG: cms:CMS_1730 putative two component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR.
       0.594
Tpau_2478
PFAM: GCN5-related N-acetyltransferase; KEGG: mgm:Mmc1_2934 GCN5-related N- acetyltransferase.
  
     0.560
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.556
Tpau_0123
KEGG: svi:Svir_26770 hypothetical protein.
  
     0.507
Tpau_0331
KEGG: msm:MSMEG_0067 hypothetical protein.
  
     0.478
Tpau_1844
KEGG: cai:Caci_5231 hypothetical protein.
  
     0.476
Tpau_0644
KEGG: sen:SACE_2591 hypothetical protein.
       0.456
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (48%) [HD]