Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: nfa:nfa51600 glutamate-1-semialdehyde aminotransferase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (439 aa)    
Predicted Functional Partners:
Tpau_0670
Porphobilinogen synthase; KEGG: rop:ROP_17220 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.990
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.988
Tpau_0071
PFAM: aminotransferase class-III; C- methyltransferase; KEGG: rha:RHA1_ro05728 glutamate-1-semialdehyde 2,1- aminomutase.
 
  
 
0.930
Tpau_3948
PFAM: aminotransferase class-III; KEGG: bmr:BMI_II1109 glutamate-1-semialdehyde 2,1- aminomutase, putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.924
Tpau_0688
PFAM: Phosphoglycerate mutase; KEGG: rer:RER_16670 hypothetical protein.
  
    0.918
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.901
Tpau_0689
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: mgi:Mflv_0052 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
  
 0.895
Tpau_3479
PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: sma:SAV_943 type I polyketide synthase AVES 4.
    
 0.874
Tpau_0690
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: rer:RER_16690 cytochrome c biogenesis protein CcdA.
  
  
 0.841
Tpau_0669
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: nfa:nfa51680 putative uroporphyrin-III C- methyltransferase/uroporphyrinogen-III synthase.
 
  
 0.823
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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