Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0728KEGG: mkm:Mkms_1259 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR. (142 aa)    
Predicted Functional Partners:
menD
Thiamine pyrophosphate protein TPP binding domain protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
       0.642
Tpau_0730
KEGG: rer:RER_17050 hypothetical protein.
       0.642
Tpau_0727
Membrane protein AbrB duplication; KEGG: msm:MSMEG_1698 putative ammonia monooxygenase superfamily protein; TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase.
 
     0.615
Tpau_0726
PFAM: Saccharopine dehydrogenase; KEGG: rha:RHA1_ro00897 hypothetical protein.
       0.562
Tpau_0731
PFAM: glycosyl transferase group 1; KEGG: rop:ROP_16690 mannosyltransferase MgtA.
       0.542
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
       0.531
Tpau_0733
Trans-hexaprenyltranstransferase; KEGG: rha:RHA1_ro01991 polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.503
Tpau_0734
PFAM: peptidase M48 Ste24p; KEGG: sen:SACE_6884 protease HtpX-like protein.
       0.478
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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