Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0795KEGG: rha:RHA1_ro01550 protein-N(pi)- phosphohistidine--sugar phosphotransferase; PFAM: phosphotransferase system EIIC. (411 aa)    
Predicted Functional Partners:
Tpau_0797
PFAM: sugar-specific permease EIIA 1 domain; KEGG: kse:Ksed_16940 PTS system N-acetylglucosamine- specific EIIA component.
 0.999
Tpau_0794
TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; KEGG: rop:ROP_12500 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase.
 
  
 0.989
Tpau_0187
KEGG: mjl:Mjls_0069 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
  
 
 0.940
Tpau_0796
PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: art:Arth_3515 phosphotransferase system PTS, EIIB protein.
 
  
 0.929
Tpau_0186
KEGG: mkm:Mkms_0089 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
  
 0.827
Tpau_0183
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 0.727
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
  
 0.675
Tpau_1879
PFAM: ROK family protein; KEGG: rop:ROP_68090 polyphosphate glucokinase.
 
 
 0.605
Tpau_2675
PFAM: ROK family protein; KEGG: nfa:nfa17130 putative sugar kinase.
  
 
 0.554
Tpau_0218
PFAM: ROK family protein; KEGG: rha:RHA1_ro02081 ROK family transcriptional regulator.
  
 
 0.548
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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