Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (344 aa)    
Predicted Functional Partners:
Tpau_0883
PFAM: peptidase M22 glycoprotease; KEGG: nfa:nfa8820 hypothetical protein.
  
 0.999
Tpau_0880
PFAM: protein of unknown function UPF0079; KEGG: rha:RHA1_ro06182 hypothetical protein.
  
 0.992
Tpau_0884
KEGG: rha:RHA1_ro06184 acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.
 
  
 0.966
Tpau_1640
KEGG: mjl:Mjls_1274 hypothetical protein.
  
 0.923
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rer:RER_32900 phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.770
Tpau_1238
Sua5/YciO/YrdC/YwlC family protein; KEGG: nfa:nfa10560 hypothetical protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; Belongs to the SUA5 family.
 
 0.687
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.681
pheS
TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; KEGG: nfa:nfa19180 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
   
 0.672
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.670
Tpau_0245
KEGG: fre:Franean1_0530 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    0.647
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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