Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa)    
Predicted Functional Partners:
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rer:RER_32900 phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.821
Tpau_0948
TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; KEGG: nfa:nfa9310 putative exonuclease; PFAM: Endonuclease/exonuclease/phosphatase.
       0.781
Tpau_0950
Ribonuclease; KEGG: msm:MSMEG_1658 ribonuclease, putative; TIGRFAM: ribonuclease; PFAM: ribonuclease BN.
       0.763
Tpau_0946
PFAM: guanine-specific ribonuclease N1 and T1; KEGG: rer:RER_20080 guanyl-specific ribonuclease.
       0.752
Tpau_0947
KEGG: fre:Franean1_5433 hypothetical protein.
       0.736
leuS
KEGG: rer:RER_59970 leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.735
argS
TIGRFAM: arginyl-tRNA synthetase; KEGG: rer:RER_39240 arginyl-tRNA synthetase.
 
  
 0.727
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.717
Tpau_0945
PFAM: major facilitator superfamily MFS_1; KEGG: mab:MAB_1429 major facilitator superfamily permease.
       0.713
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.703
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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