Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
addTIGRFAM: adenosine deaminase; KEGG: nfa:nfa9530 adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (375 aa)    
Predicted Functional Partners:
Tpau_1531
PFAM: PfkB domain protein; KEGG: rer:RER_36040 adenosine kinase.
    
 0.937
Tpau_0983
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.934
Tpau_2122
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rha:RHA1_ro07236 purine nucleosidase.
  
 
 0.917
Tpau_2145
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: rpc:RPC_1152 5'-nucleotidase-like; Belongs to the 5'-nucleotidase family.
    
 0.912
Tpau_0544
HAD-superfamily hydrolase, subfamily IIA; KEGG: rop:ROP_19480 putative NMP phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; Belongs to the HAD-like hydrolase superfamily.
     
 0.903
Tpau_2642
PFAM: protein of unknown function DUF152; KEGG: rha:RHA1_ro01084 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
 0.902
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.757
Tpau_0975
KEGG: cai:Caci_0885 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
       0.709
Tpau_0969
TIGRFAM: pyrimidine-nucleoside phosphorylase; KEGG: nca:Noca_3535 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like.
 
   
 0.670
Tpau_0968
KEGG: mjl:Mjls_1257 cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding.
 
   
 0.650
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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