Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
Tpau_0992Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: nfa:nfa9700 putative aminotransferase. (388 aa)    
Predicted Functional Partners:
Tpau_0177
D-lactate dehydrogenase (cytochrome); KEGG: rer:RER_51320 FAD-linked oxidase; PFAM: FAD linked oxidase domain protein.
    
  0.916
Tpau_0461
PFAM: aminotransferase class I and II; KEGG: rer:RER_13320 alanine aminotransferase.
   
 0.911
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.909
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.905
Tpau_1211
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: rha:RHA1_ro06012 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes.
   
 
 0.904
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.904
Tpau_1497
KEGG: rop:ROP_08930 glutamine synthetase I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
    
 0.901
Tpau_1510
KEGG: mab:MAB_1933c glutamine synthetase, type I (GlnA1); TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
    
 0.901
Tpau_2888
KEGG: rha:RHA1_ro05312 glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region.
    
 0.901
Tpau_1743
TIGRFAM: alanine dehydrogenase; KEGG: mjl:Mjls_2087 L-alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; Belongs to the AlaDH/PNT family.
    
 0.900
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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