Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_1047Integral membrane sensor signal transduction histidine kinase; KEGG: rer:RER_21360 two-component histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein. (428 aa)    
Predicted Functional Partners:
Tpau_1046
Two component transcriptional regulator, winged helix family; KEGG: rop:ROP_63600 putative OmpR family two- component response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.788
Tpau_1048
PFAM: GtrA family protein; KEGG: rha:RHA1_ro06298 hypothetical protein.
 
     0.761
Tpau_1263
Myosin; KEGG: rha:RHA1_ro01457 myosin.
  
     0.669
Tpau_0693
KEGG: rer:RER_16740 hypothetical protein; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR.
  
     0.666
Tpau_0830
KEGG: nfa:nfa6440 hypothetical protein.
 
     0.653
Tpau_0904
KEGG: rer:RER_19310 hypothetical protein.
 
    0.597
Tpau_1076
Two component transcriptional regulator, winged helix family; KEGG: mjl:Mjls_1381 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.569
Tpau_0097
KEGG: rer:RER_19460 OmpR family two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.544
Tpau_1622
KEGG: rha:RHA1_ro00074 response regulator, two- component system; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.529
Tpau_0119
TIGRFAM: RecB family nuclease, putative; KEGG: nfa:nfa1140 hypothetical protein.
  
     0.512
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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