Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1048PFAM: GtrA family protein; KEGG: rha:RHA1_ro06298 hypothetical protein. (194 aa)    
Predicted Functional Partners:
Tpau_1047
Integral membrane sensor signal transduction histidine kinase; KEGG: rer:RER_21360 two-component histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein.
 
     0.761
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.670
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.670
Tpau_2679
KEGG: rop:ROP_08480 hypothetical protein.
  
     0.669
Tpau_0828
KEGG: mva:Mvan_5040 major facilitator superfamily transporter.
  
     0.661
Tpau_3115
KEGG: mav:MAV_1229 hypothetical protein.
  
     0.659
Tpau_2805
KEGG: rha:RHA1_ro01294 hypothetical protein.
  
     0.636
Tpau_1300
KEGG: mav:MAV_1560 hypothetical protein.
  
     0.632
Tpau_1127
KEGG: mab:MAB_3524c hypothetical protein.
  
     0.630
Tpau_2840
KEGG: rer:RER_24170 hypothetical protein.
  
     0.619
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.