Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1055PFAM: phosphoesterase PA-phosphatase related; KEGG: rha:RHA1_ro08681 hypothetical protein. (199 aa)    
Predicted Functional Partners:
Tpau_1057
KEGG: rha:RHA1_ro08683 hypothetical protein.
       0.783
Tpau_1056
KEGG: rha:RHA1_ro08682 hypothetical protein.
       0.773
Tpau_1058
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: mab:MAB_3618c acyl-CoA dehydrogenase FadE.
       0.460
Tpau_3481
PFAM: NDP-hexose 23-dehydratase; KEGG: svi:Svir_29870 NDP-hexose 2,3-dehydratase.
  
     0.448
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
 
 
 
 0.415
Tpau_1489
PFAM: ribonuclease II; KEGG: rha:RHA1_ro01172 ribonuclease R.
 
 
  0.411
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
 
 
 
 0.411
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.407
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (20%) [HD]