Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_1099Transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; KEGG: rha:RHA1_ro05652 redox-sensitive transcriptional activator; SMART: regulatory protein MerR. (151 aa)    
Predicted Functional Partners:
Tpau_1100
PFAM: protein of unknown function DUF159; KEGG: nfa:nfa45870 hypothetical protein; Belongs to the SOS response-associated peptidase family.
       0.776
Tpau_1098
KEGG: mav:MAV_2859 ModD protein.
       0.669
Tpau_1096
GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.490
Tpau_0215
PFAM: protein of unknown function DUF1006; KEGG: kse:Ksed_08640 hypothetical protein.
  
     0.486
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.483
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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