Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Tpau_1108TIGRFAM: anti-sigma factor; KEGG: nfa:nfa45830 putative anti-sigma factor. (93 aa)    
Predicted Functional Partners:
Tpau_1107
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rop:ROP_64020 RNA polymerase ECF-type sigma factor SigH; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein.
  
 
 0.962
Tpau_3548
KEGG: rer:RER_48110 hypothetical protein.
  
     0.704
Tpau_0628
PFAM: Protein of unknown function DUF2596; KEGG: rha:RHA1_ro02072 hypothetical protein.
  
     0.690
Tpau_1109
KEGG: rer:RER_21890 two-component histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
     0.630
Tpau_3911
KEGG: rer:RER_05010 hypothetical protein.
  
     0.621
Tpau_1395
KEGG: rer:RER_38230 hypothetical protein.
 
    0.581
Tpau_1105
ybaK/ebsC protein; KEGG: aau:AAur_1805 putative YbaK/EbsC protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.556
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.552
Tpau_2759
KEGG: mjl:Mjls_3464 hypothetical protein.
 
     0.529
Tpau_1106
KEGG: mav:MAV_3285 hypothetical protein.
       0.522
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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