Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylateN-su ccinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (316 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.970
Tpau_0804
PFAM: aminotransferase class I and II; KEGG: nfa:nfa6260 aminotransferase.
  
 
 0.952
argD
KEGG: rop:ROP_06840 acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
    
 0.919
Tpau_1160
KEGG: rop:ROP_60240 succinyl-diaminopimelate desuccinylase; TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
   
 0.896
Tpau_1152
KEGG: rop:ROP_60090 succinyldiaminopimelate aminotransferase; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: aminotransferase class I and II.
 
 
 0.826
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.736
Tpau_1161
PFAM: conserved hypothetical protein; KEGG: rer:RER_41700 hypothetical protein; Belongs to the LOG family.
       0.651
Tpau_1162
PFAM: conserved hypothetical protein; KEGG: rop:ROP_60260 hypothetical protein; Belongs to the LOG family.
       0.651
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.643
Tpau_1165
PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase.
     
 0.639
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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