Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1164Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (287 aa)    
Predicted Functional Partners:
Tpau_0563
TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK.
 
 
 0.997
Tpau_0562
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.991
Tpau_1469
TIGRFAM: FolC bifunctional protein; KEGG: nfa:nfa13490 putative folylpolyglutamate synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein.
 
 0.989
folE
TIGRFAM: GTP cyclohydrolase I; KEGG: mjl:Mjls_5155 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
 0.930
Tpau_0561
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
0.923
Tpau_3571
PFAM: aminotransferase class IV; KEGG: rop:ROP_49290 putative aminotransferase.
  
 
 0.920
Tpau_1165
PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase.
  
  
 0.882
Tpau_1162
PFAM: conserved hypothetical protein; KEGG: rop:ROP_60260 hypothetical protein; Belongs to the LOG family.
       0.792
Tpau_1161
PFAM: conserved hypothetical protein; KEGG: rer:RER_41700 hypothetical protein; Belongs to the LOG family.
       0.790
Tpau_1166
Hypothetical protein.
       0.776
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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