Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1165PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase. (302 aa)    
Predicted Functional Partners:
Tpau_1160
KEGG: rop:ROP_60240 succinyl-diaminopimelate desuccinylase; TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
  
 
 0.898
Tpau_1161
PFAM: conserved hypothetical protein; KEGG: rer:RER_41700 hypothetical protein; Belongs to the LOG family.
     
 0.883
Tpau_1164
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.882
Tpau_1162
PFAM: conserved hypothetical protein; KEGG: rop:ROP_60260 hypothetical protein; Belongs to the LOG family.
     
 0.793
Tpau_1166
Hypothetical protein.
       0.776
Tpau_1163
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro05967 acyl-CoA synthetase.
   
   0.750
Tpau_1159
Magnesium transporter; Acts as a magnesium transporter.
       0.674
dapD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylateN-su ccinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
     
 0.639
Tpau_2918
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rer:RER_23720 methyltransferase.
 
   
 0.602
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
  
 0.597
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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