Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1181PFAM: NUDIX hydrolase; KEGG: rer:RER_21510 hypothetical protein. (185 aa)    
Predicted Functional Partners:
Tpau_1182
KEGG: mav:MAV_4225 F420-0--gamma-glutamyl ligase; TIGRFAM: F420 biosynthesis protein FbiB, C-terminal domain; F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; nitroreductase.
     0.920
Tpau_1183
LPPG domain protein containing protein; KEGG: rop:ROP_63740 LPPG--FO 2-phopspho-L-lactate transferase; TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD.
       0.836
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
  
 0.657
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.540
Tpau_0659
KEGG: rop:ROP_17330 hypothetical protein.
  
 
  0.532
deaD
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
  
 0.493
Tpau_1489
PFAM: ribonuclease II; KEGG: rha:RHA1_ro01172 ribonuclease R.
   
 0.428
Tpau_1315
PFAM: MaoC domain protein dehydratase; Beta- ketoacyl synthase; Acyl transferase; domain of unknown function DUF1729; KEGG: nfa:nfa12570 putative fatty acid synthase.
  
  0.427
Tpau_3625
Putative transcriptional regulator, TetR family; KEGG: nfa:nfa5580 hypothetical protein.
  
     0.424
Tpau_1118
DEAD/DEAH box helicase domain protein; KEGG: rop:ROP_64170 putative ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; Belongs to the DEAD box helicase family.
   
 0.423
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.