Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1189TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: mgi:Mflv_4724 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I. (407 aa)    
Predicted Functional Partners:
Tpau_1187
Phosphomannomutase; KEGG: rha:RHA1_ro06316 phosphomannomutase/phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
  
 
 0.987
pgi
KEGG: rha:RHA1_ro05567 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
 
 
 0.946
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.940
Tpau_0982
Glucose-1,6-bisphosphate synthase; KEGG: rop:ROP_63170 putative phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
  
 
 0.914
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.912
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
     
 0.907
Tpau_0525
PFAM: PfkB domain protein; KEGG: kse:Ksed_20450 sugar kinase, ribokinase.
    
 0.905
Tpau_3119
TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: rer:RER_42390 fructose 1,6-bisphosphatase class II; PFAM: GlpX family protein.
     
 0.901
Tpau_1188
KEGG: rop:ROP_63790 hypothetical protein.
  
    0.888
Tpau_0186
KEGG: mkm:Mkms_0089 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
  
  
 0.850
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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