Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1268PFAM: Thioredoxin domain; KEGG: rer:RER_38920 hypothetical protein. (323 aa)    
Predicted Functional Partners:
Tpau_0406
PFAM: response regulator receiver; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rer:RER_40230 two-component system thioredoxin reductase; SMART: response regulator receiver.
  
 
 0.713
Tpau_4232
KEGG: mva:Mvan_6067 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein.
  
 
 0.640
Tpau_0669
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: nfa:nfa51680 putative uroporphyrin-III C- methyltransferase/uroporphyrinogen-III synthase.
  
  
 0.582
Tpau_1266
KEGG: rer:RER_38930 hypothetical protein.
       0.576
Tpau_2969
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.576
Tpau_2330
KEGG: mab:MAB_2408c hypothetical protein.
   
    0.564
Tpau_1269
PFAM: extracellular solute-binding protein family 1; KEGG: ami:Amir_4241 extracellular solute-binding protein family 1.
     
 0.559
Tpau_1270
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sma:SAV_2093 sugar ABC transporter permeases protein.
       0.557
Tpau_1271
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sma:SAV_2094 sugar ABC transporter permeases protein.
       0.557
Tpau_1267
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro00948 acyl-CoA synthetase.
       0.541
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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