Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1350Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: cmi:CMM_2877 putative two-component system, sensor kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (543 aa)    
Predicted Functional Partners:
Tpau_1351
KEGG: cgt:cgR_0089 hypothetical protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.972
Tpau_3597
Response regulator receiver and unknown domain protein; KEGG: rha:RHA1_ro04820 regulator relate; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.890
Tpau_1349
citrate/H+ symporter, CitMHS family; KEGG: rer:RER_13860 citrate transporter; TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: Citrate transporter.
 
   
 0.846
Tpau_1352
KEGG: msm:MSMEG_2381 hypothetical protein.
       0.570
Tpau_1353
PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; dienelactone hydrolase; KEGG: mva:Mvan_5922 peptidase S9 prolyl oligopeptidase.
       0.429
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (26%) [HD]