Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1366KEGG: cmi:CMM_0775 putative aldolase. (316 aa)    
Predicted Functional Partners:
Tpau_1368
PFAM: Myo-inositol catabolism IolB domain protein; KEGG: cgb:cg0201 hypothetical protein.
 
  
 0.954
Tpau_1365
PFAM: PfkB domain protein; KEGG: cmi:CMM_0774 putative sugar kinase.
 
   
 0.953
Tpau_1369
PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: cmi:CMM_0778 putative acetolactate synthase; Belongs to the TPP enzyme family.
 
    0.949
Tpau_1364
KEGG: rer:RER_20220 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
 
     0.865
Tpau_1367
KEGG: cmi:CMM_0776 putative NAD-dependent aldehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
 
  
 0.826
Tpau_1362
Myo-inosose-2 dehydratase; KEGG: rha:RHA1_ro01363 sugar phosphate isomerase/epimerase IolE; PFAM: Xylose isomerase domain protein TIM barrel.
 
    0.793
Tpau_1358
KEGG: rop:ROP_05200 putative ABC transporter substrate-binding protein.
 
  
 0.578
Tpau_1357
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sco:SCO6988 oxidoreductase.
 
     0.470
Tpau_1361
Inositol 2-dehydrogenase; KEGG: cgt:cgR_2947 hypothetical protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain.
 
     0.451
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (20%) [HD]