Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_1392TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: tmz:Tmz1t_1382 diguanylate cyclase with PAS/PAC sensor; SMART: GGDEF domain containing protein; PAC repeat- containing protein; PAS domain containing protein. (483 aa)    
Predicted Functional Partners:
Tpau_2112
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: rca:Rcas_3136 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.875
Tpau_0406
PFAM: response regulator receiver; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rer:RER_40230 two-component system thioredoxin reductase; SMART: response regulator receiver.
  
 
 0.872
Tpau_2057
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mab:MAB_1867 hypothetical protein; SMART: GGDEF domain containing protein.
 
 
 
 0.800
Tpau_0094
KEGG: mgi:Mflv_3888 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.792
Tpau_0407
Histidine kinase; KEGG: rer:RER_40240 two-component histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein.
 
 0.713
Tpau_0653
Histidine kinase; KEGG: mab:MAB_4048c sensor-like histidine kinase senX3; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
 
 0.603
Tpau_3590
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: nfa:nfa11350 hypothetical protein; SMART: GGDEF domain containing protein.
 
0.576
Tpau_1391
PFAM: globin; KEGG: mva:Mvan_4066 globin.
     
 0.575
Tpau_1913
PFAM: glycosyl transferase family 2; KEGG: rer:RER_18450 glycosyltransferase.
  
  
 0.532
Tpau_3630
Integral membrane sensor signal transduction histidine kinase; KEGG: rer:RER_09880 two-component histidine kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 0.500
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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