Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_1411Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: rha:RHA1_ro05271 sensor kinase, two-component system. (386 aa)    
Predicted Functional Partners:
Tpau_1410
KEGG: rop:ROP_53160 putative NarL family two- component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.950
Tpau_2872
KEGG: rer:RER_23880 NarL family two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; sigma-70 region 4 domain protein; SMART: regulatory protein LuxR; response regulator receiver.
 
 
 0.777
Tpau_0647
Two component transcriptional regulator, LuxR family; KEGG: cms:CMS_1730 putative two component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.739
Tpau_0972
KEGG: saq:Sare_0423 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.738
Tpau_2494
KEGG: ami:Amir_4995 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.737
Tpau_1009
Two component transcriptional regulator, LuxR family; KEGG: svi:Svir_39200 response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.735
Tpau_1874
KEGG: bcv:Bcav_0335 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.729
Tpau_1989
Two component transcriptional regulator, LuxR family; KEGG: sco:SCO4363 two component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver.
 
 
 0.726
Tpau_0971
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: ami:Amir_0531 histidine kinase.
  
     0.725
Tpau_3507
KEGG: rop:ROP_64570 putative NarL family two- component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.720
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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