Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1418KEGG: rop:ROP_33220 putative Xre family DNA-binding protein; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein. (203 aa)    
Predicted Functional Partners:
Tpau_1417
Agmatinase; KEGG: rer:RER_05760 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.
 
   
 0.753
Tpau_1415
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: rer:RER_05780 hydrolase.
  
  
 0.580
Tpau_1414
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rha:RHA1_ro03531 tryptophan 2-monooxygenase.
     
 0.560
Tpau_1416
PFAM: amino acid permease-associated region; KEGG: rha:RHA1_ro03529 amino acid transporter.
     
 0.560
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.550
Tpau_1453
Transcriptional regulator, XRE family; KEGG: mab:MAB_0769c putative transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.
  
  
 0.538
Tpau_0107
KEGG: rop:ROP_35350 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II.
     
 0.518
Tpau_2101
KEGG: aau:AAur_1207 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
 
  
 0.491
Tpau_2968
PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rha:RHA1_ro04506 xanthine dehydrogenase molybdenum binding subunit.
  
  
 0.444
Tpau_0801
KEGG: rer:RER_39640 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
  
 0.424
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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