Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1426PFAM: Bifunctional DNA primase/polymerase; KEGG: bln:Blon_1128 pancreatic ribonuclease. (808 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 
 0.832
Tpau_1427
Hypothetical protein.
       0.773
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
 
 0.688
Tpau_2959
PFAM: MMPL domain protein; KEGG: mab:MAB_1137c MmpL family protein.
  
   
 0.610
Tpau_3894
PFAM: protein of unknown function DUF1483; KEGG: mkm:Mkms_2957 hypothetical protein.
  
     0.579
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.551
Tpau_3898
PFAM: major capsid protein HK97; KEGG: mkm:Mkms_2954 phage major capsid protein, HK97.
 
   
 0.546
Tpau_0222
PFAM: IstB domain protein ATP-binding protein; KEGG: art:Arth_1779 IstB ATP binding domain- containing protein; Belongs to the DnaA family.
  
 
 0.515
Tpau_1025
KEGG: lxx:Lxx22700 transposase; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase.
  
 
 0.515
Tpau_1870
PFAM: IstB domain protein ATP-binding protein; KEGG: art:Arth_1779 IstB ATP binding domain- containing protein.
  
 
 0.515
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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