Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_1477KEGG: mab:MAB_0929 hypothetical protein. (335 aa)    
Predicted Functional Partners:
Tpau_2746
PFAM: regulatory protein TetR; KEGG: rer:RER_07500 TetR family transcriptional regulator.
  
     0.705
Tpau_0414
KEGG: rha:RHA1_ro05188 hypothetical protein.
  
     0.632
Tpau_2945
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rer:RER_56310 ferredoxin--NADP(+) reductase.
 
    0.584
Tpau_3703
PFAM: Polyketide cyclase/dehydrase; KEGG: rop:ROP_18720 hypothetical protein.
  
     0.557
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.539
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.539
Tpau_0418
PFAM: coagulation factor 5/8 type domain protein; KEGG: rha:RHA1_ro05192 hypothetical protein.
  
     0.512
Tpau_1478
KEGG: nfa:nfa11710 putative Clp protease proteolytic subunit; PFAM: peptidase S14 ClpP; Belongs to the peptidase S14 family.
       0.506
clpP-3
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.506
Tpau_0401
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rha:RHA1_ro05186 methyltransferase.
  
     0.503
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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