Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Tpau_1492TIGRFAM: proline iminopeptidase; KEGG: rop:ROP_08970 prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family. (330 aa)    
Predicted Functional Partners:
Tpau_4229
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ckp:ckrop_0287 delta-1-pyrroline-5- carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.903
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.901
Tpau_1491
PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: ami:Amir_1092 CHAD domain containing protein.
       0.836
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.836
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
   0.610
Tpau_3412
PFAM: TAP domain protein; KEGG: nfa:nfa55080 putative hydrolase.
 
     0.460
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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