Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1501PFAM: peptidylprolyl isomerase FKBP-type; KEGG: mab:MAB_2559c peptidyl-prolyl cis-trans isomerase. (183 aa)    
Predicted Functional Partners:
Tpau_1502
PFAM: Methyltransferase type 12; Methyltransferase type 11; methyltransferase small; KEGG: kse:Ksed_01410 methylase involved in ubiquinone/menaquinone biosynthesis.
  
    0.651
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.583
Tpau_1500
KEGG: nfa:nfa27990 hypothetical protein.
       0.561
Tpau_3982
KEGG: rha:RHA1_ro04291 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
    
   0.523
Tpau_1589
KEGG: lmc:Lm4b_00680 hypothetical protein.
   
 0.517
htpG
Heat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity.
   
 0.517
Tpau_1811
TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; KEGG: nfa:nfa37970 putative ATP-dependent helicase; SMART: DEAD-like helicase; helicase domain protein; AAA ATPase.
 
 0.515
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.456
Tpau_3378
KEGG: nfa:nfa8520 hypothetical protein.
   
 0.456
Tpau_0022
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.455
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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