Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1543PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: dhd:Dhaf_3417 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (347 aa)    
Predicted Functional Partners:
Tpau_1544
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sus:Acid_5133 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
    
0.838
Tpau_1546
PFAM: aconitate hydratase domain protein; KEGG: scl:sce0086 isopropylmalate isomerase large subunit.
     
 0.784
Tpau_1545
PFAM: aconitate hydratase domain protein; KEGG: syd:Syncc9605_0257 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family.
       0.776
Tpau_1547
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bbt:BBta_2283 putative short-chain dehydrogenase/reductase.
 
 
   0.709
Tpau_1542
KEGG: bcj:BCAM0069 hypothetical protein.
       0.671
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
  
 0.548
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
  
 0.523
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
 
   0.496
Tpau_3762
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
 
 0.493
Tpau_1548
KEGG: mab:MAB_1173c hypothetical protein.
       0.439
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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