Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_1571PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. (95 aa)    
Predicted Functional Partners:
Tpau_3762
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.942
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.917
Tpau_0284
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: msm:MSMEG_3964 pyruvate dehydrogenase; Belongs to the TPP enzyme family.
     
 0.904
Tpau_4058
KEGG: rop:ROP_61390 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.904
Tpau_3071
PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase.
     
 0.903
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.903
Tpau_0557
PFAM: Amidase; KEGG: rha:RHA1_ro04406 amidase.
    
  0.902
Tpau_0680
PFAM: Amidase; KEGG: mkm:Mkms_5239 amidase.
    
  0.902
Tpau_0789
PFAM: Amidase; KEGG: nfa:nfa33260 amidase; Belongs to the amidase family.
    
  0.902
Tpau_2035
PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein.
     
  0.900
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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