Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_1718PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rer:RER_26350 hypothetical protein. (314 aa)    
Predicted Functional Partners:
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.944
Tpau_1719
MATE efflux family protein; KEGG: nfa:nfa40630 putative DNA-damage-inducible protein F; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.
 
   
 0.896
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.779
Tpau_1720
KEGG: predicted protein.
       0.655
disA
Protein of unknown function DUF147; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
  
   
 0.634
Tpau_1716
PFAM: protein of unknown function DUF503; KEGG: nfa:nfa40660 hypothetical protein.
       0.620
Tpau_1714
PFAM: protein of unknown function DUF448; KEGG: rha:RHA1_ro06643 hypothetical protein.
  
    0.556
orn
Exonuclease RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
     
 0.550
Tpau_0860
PFAM: carboxyl transferase; KEGG: rer:RER_45670 acetyl-CoA carboxylase beta chain.
 
     0.518
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.512
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.