Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1719MATE efflux family protein; KEGG: nfa:nfa40630 putative DNA-damage-inducible protein F; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE. (441 aa)    
Predicted Functional Partners:
Tpau_1718
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rer:RER_26350 hypothetical protein.
 
   
 0.896
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
     
 0.882
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
     
 0.746
Tpau_0472
PFAM: Squalene/phytoene synthase; KEGG: krh:KRH_20840 phytoene synthase.
   
  
 0.706
Tpau_2540
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: mab:MAB_2779c glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.663
Tpau_1720
KEGG: predicted protein.
       0.656
Tpau_1716
PFAM: protein of unknown function DUF503; KEGG: nfa:nfa40660 hypothetical protein.
       0.620
Tpau_1714
PFAM: protein of unknown function DUF448; KEGG: rha:RHA1_ro06643 hypothetical protein.
   
   0.550
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.539
Tpau_2435
PFAM: RNA binding S1 domain protein; KEGG: nfa:nfa18970 30S ribosomal protein S1.
  
    0.536
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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