Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1752KEGG: cai:Caci_2076 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family. (424 aa)    
Predicted Functional Partners:
Tpau_1753
KEGG: msm:MSMEG_1855 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat.
  
 0.867
Tpau_1832
Histone deacetylase; KEGG: rer:RER_28020 acetoin utilization protein; PFAM: histone deacetylase superfamily.
   
 0.728
Tpau_1751
PFAM: MMPL domain protein; KEGG: mjl:Mjls_4293 MmpL domain-containing protein.
 
     0.722
Tpau_1749
L-lysine 6-monooxygenase (NADPH); KEGG: cur:cur_0328 putative L-ornithine N5- oxygenase.
       0.686
Tpau_1750
KEGG: mab:MAB_1936 hypothetical protein.
       0.686
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.685
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.637
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.631
Tpau_0245
KEGG: fre:Franean1_0530 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
     0.612
Tpau_1968
KEGG: mgi:Mflv_0116 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
     0.591
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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