Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1777Helix-turn-helix domain protein; KEGG: rop:ROP_67420 putative Xre family DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. (91 aa)    
Predicted Functional Partners:
Tpau_1882
KEGG: mab:MAB_3005c hypothetical protein.
  
     0.701
Tpau_1778
Phage shock protein A, PspA; PFAM: PspA/IM30 family protein; KEGG: mab:MAB_3067c hypothetical protein.
  
  
 0.682
Tpau_2801
PFAM: DNA polymerase III delta; KEGG: nfa:nfa13940 hypothetical protein.
  
     0.678
Tpau_2639
PFAM: protein of unknown function YGGT; KEGG: rop:ROP_08090 hypothetical membrane protein.
  
     0.665
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
    0.651
Tpau_2336
Transcriptional regulator, MerR family; SMART: regulatory protein MerR; KEGG: mab:MAB_2406 putative HTH-type transcriptional regulator.
  
    0.627
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.612
Tpau_1776
PFAM: CinA domain protein; KEGG: svi:Svir_25150 competence/damage-inducible protein CinA; Belongs to the CinA family.
     
 0.612
Tpau_1775
KEGG: sen:SACE_5881 CDP-diacylglycerol--glycerol-3- phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.590
Tpau_3040
KEGG: rer:RER_22280 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342.
  
     0.588
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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