Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1796PFAM: protein of unknown function DUF349; KEGG: rer:RER_27610 hypothetical protein. (448 aa)    
Predicted Functional Partners:
Tpau_1795
SMART: AAA ATPase; KEGG: fal:FRAAL1799 putative ABC transporter.
       0.778
Tpau_1882
KEGG: mab:MAB_3005c hypothetical protein.
  
     0.750
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.746
Tpau_1512
KEGG: rop:ROP_08820 hypothetical membrane protein.
  
     0.732
Tpau_2801
PFAM: DNA polymerase III delta; KEGG: nfa:nfa13940 hypothetical protein.
 
   
 0.726
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.705
Tpau_3577
KEGG: rop:ROP_49220 hypothetical protein.
  
     0.697
Tpau_3046
KEGG: mab:MAB_3511c DNA helicase II; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein.
 
 
 0.694
Tpau_2336
Transcriptional regulator, MerR family; SMART: regulatory protein MerR; KEGG: mab:MAB_2406 putative HTH-type transcriptional regulator.
  
     0.691
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
   
   0.689
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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