Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Tpau_1814KEGG: rer:RER_45270 acetate permease; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (545 aa)    
Predicted Functional Partners:
Tpau_1813
PFAM: protein of unknown function DUF485; KEGG: bcv:Bcav_3374 protein of unknown function DUF485.
 
  
 0.997
Tpau_1742
KEGG: mkm:Mkms_2510 cyclic nucleotide-binding protein; PFAM: protein of unknown function DUF294 nucleotidyltransferase putative; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; CBS domain containing protein; SMART: CBS domain containing protein.
 
  
 0.569
Tpau_3762
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.531
Tpau_1812
PFAM: aminotransferase class-III; KEGG: rha:RHA1_ro06796 adenosylmethionine-8-amino-7- oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
    0.530
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.486
Tpau_0855
TIGRFAM: citrate synthase I; KEGG: rha:RHA1_ro04998 type II citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.457
Tpau_2671
PFAM: AMP-dependent synthetase and ligase; KEGG: svi:Svir_32550 acyl-CoA synthetase/AMP-acid ligase.
  
  
 0.425
Tpau_3071
PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase.
  
  
 0.425
Tpau_3315
KEGG: mab:MAB_4376c putative acetoacetyl-CoA synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase.
  
  
 0.417
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.404
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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