Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1825PFAM: protein of unknown function DUF75; KEGG: rop:ROP_67900 hypothetical protein. (311 aa)    
Predicted Functional Partners:
Tpau_1824
PFAM: alpha/beta hydrolase fold; KEGG: mkm:Mkms_2218 alpha/beta hydrolase fold.
       0.778
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.605
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.601
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.582
Tpau_1823
PFAM: alpha/beta hydrolase fold; KEGG: mav:MAV_3609 hydrolase.
       0.581
Tpau_1821
KEGG: rop:ROP_67880 putative helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
       0.576
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.534
Tpau_1826
KEGG: rer:RER_52300 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.
       0.525
Tpau_1633
PFAM: Protein of unknown function DUF2469; KEGG: rop:ROP_65970 hypothetical protein.
  
     0.487
Tpau_0907
TIGRFAM: IMP dehydrogenase family protein; KEGG: rha:RHA1_ro06200 inosine 5-monophosphate dehydrogenase.
  
     0.478
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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