Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1864PFAM: AMP-dependent synthetase and ligase; KEGG: cai:Caci_4379 AMP-dependent synthetase and ligase. (506 aa)    
Predicted Functional Partners:
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 0.930
Tpau_1315
PFAM: MaoC domain protein dehydratase; Beta- ketoacyl synthase; Acyl transferase; domain of unknown function DUF1729; KEGG: nfa:nfa12570 putative fatty acid synthase.
  
 
 0.927
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
 
 0.885
Tpau_1860
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: nfa:nfa34080 putative acyl-CoA dehydrogenase.
  
 
 0.841
Tpau_1861
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: svi:Svir_16750 acyl-CoA dehydrogenase.
  
 
 0.841
Tpau_1862
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: rop:ROP_12060 putative acyl-CoA dehydrogenase.
  
 
 0.841
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
  
 0.837
Tpau_1031
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rer:RER_21210 acyl-CoA carboxylase alpha chain.
  
 
 0.819
Tpau_2193
TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; KEGG: nfa:nfa52820 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; Belongs to the thiolase-like superfamily. FabH family.
    
 0.807
Tpau_3478
PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: sen:SACE_4141 type I modular polyketide synthase.
 
 0.782
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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