Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1866PFAM: regulatory protein TetR; KEGG: rop:ROP_23970 putative TetR family transcriptional regulator. (207 aa)    
Predicted Functional Partners:
Tpau_1865
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: rop:ROP_12170 putative MFS transporter.
       0.623
Tpau_2325
PFAM: cytochrome b5; fatty acid desaturase; KEGG: nfa:nfa49300 hypothetical protein.
  
    0.602
Tpau_0703
KEGG: rop:ROP_23560 hypothetical protein.
  
     0.535
Tpau_2082
Enoyl-(acyl-carrier-protein) reductase (NADH); KEGG: nfa:nfa34760 enoyl-(acyl carrier protein) reductase.
      
 0.534
mshA
UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
      
 0.512
Tpau_1855
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rha:RHA1_ro01498 quinone oxidoreductase.
 
     0.453
Tpau_2367
PFAM: Mammalian cell entry related domain protein; KEGG: nfa:nfa11150 putative Mce family protein.
  
     0.450
Tpau_2973
PFAM: regulatory protein TetR; KEGG: rha:RHA1_ro06435 TetR family transcriptional regulator.
  
    0.434
Tpau_1858
Enoyl-CoA hydratase; KEGG: sma:SAV_6603 hypothetical protein; PFAM: MaoC domain protein dehydratase.
 
     0.413
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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