Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_1933PFAM: VanW family protein; KEGG: nfa:nfa54560 hypothetical protein. (567 aa)    
Predicted Functional Partners:
Tpau_1932
PFAM: protein of unknown function DUF28; KEGG: rop:ROP_68700 hypothetical protein.
       0.571
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.562
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.554
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.554
Tpau_0913
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: nfa:nfa9000 hypothetical protein.
  
     0.548
Tpau_0119
TIGRFAM: RecB family nuclease, putative; KEGG: nfa:nfa1140 hypothetical protein.
  
     0.541
Tpau_1951
KEGG: rha:RHA1_ro06905 hypothetical protein.
  
     0.500
Tpau_0423
PFAM: glycoside hydrolase family 3 domain protein; KEGG: rop:ROP_52460 putative glycosidase.
     
 0.499
Tpau_3973
PFAM: penicillin-binding protein transpeptidase; KEGG: msm:MSMEG_6319 penicillin-binding protein, transpeptidase.
  
     0.487
Tpau_1931
Acyltransferase, WS/DGAT/MGAT; KEGG: rha:RHA1_ro01601 hypothetical protein; TIGRFAM: acyltransferase, WS/DGAT/MGAT; PFAM: protein of unknown function UPF0089; Belongs to the long-chain O-acyltransferase family.
       0.466
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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