Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (418 aa)    
Predicted Functional Partners:
Tpau_1978
Shikimate-5-dehydrogenase; KEGG: rop:ROP_69190 shikimate dehydrogenase; TIGRFAM: shikimate-5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.
  
    0.923
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.887
Tpau_1976
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
    0.850
Tpau_1980
PFAM: peptidase A24A prepilin type IV; KEGG: mva:Mvan_2644 peptidase A24A, prepilin type IV.
 
     0.839
Tpau_1979
KEGG: mkm:Mkms_2777 thioesterase superfamily protein.
       0.778
Tpau_3939
Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; PASTA domain containing protein; penicillin-binding protein transpeptidase; KEGG: rer:RER_04630 penicillin-binding protein 1; SMART: PASTA domain containing protein.
 
  
 0.770
Tpau_1974
AAA ATPase central domain protein; KEGG: rop:ROP_69150 putative AAA family ATPase; PFAM: AAA ATPase central domain protein; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
  
    0.747
Tpau_1973
KEGG: rop:ROP_69140 hypothetical protein.
       0.713
Tpau_4192
Peptidoglycan glycosyltransferase; KEGG: nfa:nfa55570 putative penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase.
 
   
 0.608
Tpau_1981
KEGG: msm:MSMEG_2177 fmnh2-utilizing oxygenase.
       0.605
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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