Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2056TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mab:MAB_0124 hypothetical protein; SMART: GGDEF domain containing protein. (393 aa)    
Predicted Functional Partners:
Tpau_2112
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: rca:Rcas_3136 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.861
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.648
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.648
Tpau_2057
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mab:MAB_1867 hypothetical protein; SMART: GGDEF domain containing protein.
 
    
0.640
Tpau_2050
Extracellular solute-binding protein family 3; KEGG: sgr:SGR_5758 putative ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3.
     
 0.474
Tpau_2051
KEGG: sgr:SGR_5757 putative ABC transporter ATP- binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.472
Tpau_2052
KEGG: kra:Krad_0928 polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component.
       0.472
Tpau_2053
PFAM: FR47 domain protein; GCN5-related N- acetyltransferase; KEGG: rha:RHA1_ro01753 acetyltransferase.
       0.472
Tpau_2058
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mab:MAB_0124 hypothetical protein; SMART: GGDEF domain containing protein.
 
    
0.467
Tpau_1392
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: tmz:Tmz1t_1382 diguanylate cyclase with PAS/PAC sensor; SMART: GGDEF domain containing protein; PAC repeat- containing protein; PAS domain containing protein.
 
 
 
0.414
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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