Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2124TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; KEGG: afw:Anae109_0595 carbohydrate kinase; PFAM: shikimate kinase. (174 aa)    
Predicted Functional Partners:
Tpau_1596
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 0.992
Tpau_0004
6-phosphogluconate dehydrogenase, decarboxylating; KEGG: mab:MAB_0003 6-phosphogluconate dehydrogenase- like protein; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein.
  
 0.991
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 
 0.915
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
 
 0.913
Tpau_3004
KEGG: rop:ROP_21910 gluconate permease; TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter.
 
  
 0.715
Tpau_2123
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nfa:nfa25540 putative short chain dehydrogenase.
     
 0.572
Tpau_2120
KEGG: sen:SACE_3690 hypothetical protein.
       0.458
Tpau_2121
KEGG: sen:SACE_3425 hypothetical protein.
       0.458
Tpau_2122
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rha:RHA1_ro07236 purine nucleosidase.
       0.458
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.426
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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