Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2148PFAM: conserved hypothetical protein; KEGG: msm:MSMEG_5823 membrane-spanning protein. (629 aa)    
Predicted Functional Partners:
Tpau_3058
PFAM: Abortive infection protein; KEGG: mab:MAB_0497 hypothetical protein.
 
     0.733
hisE
KEGG: msm:MSMEG_4181 phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase.
       0.568
Tpau_2147
Hypothetical protein; KEGG: similar to H02F09.3.
       0.551
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.517
Tpau_2204
PFAM: Abortive infection protein; KEGG: nfa:nfa5750 hypothetical protein.
 
     0.503
Tpau_0365
KEGG: nfa:nfa54850 hypothetical protein.
  
     0.455
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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