| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tpau_2178 | Tpau_2179 | Tpau_2178 | Tpau_2179 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.998 |
| Tpau_2178 | Tpau_2180 | Tpau_2178 | Tpau_2180 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | TIGRFAM: precorrin-6x reductase; KEGG: nfa:nfa31540 precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.999 |
| Tpau_2178 | Tpau_2190 | Tpau_2178 | Tpau_2190 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | precorrin-3B C17-methyltransferase; KEGG: rer:RER_31440 precorrin-2 C(20)- methyltransferase/precorrin-3B C(17)-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.996 |
| Tpau_2178 | Tpau_2191 | Tpau_2178 | Tpau_2191 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | KEGG: nfa:nfa31510 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH. | 0.999 |
| Tpau_2178 | Tpau_2196 | Tpau_2178 | Tpau_2196 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | TIGRFAM: cobaltochelatase, CobN subunit; KEGG: rha:RHA1_ro00171 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase. | 0.959 |
| Tpau_2178 | Tpau_3353 | Tpau_2178 | Tpau_3353 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | TIGRFAM: precorrin-6A synthase (deacetylating); KEGG: cai:Caci_6988 precorrin-6A synthase (deacetylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.946 |
| Tpau_2178 | cobB-3 | Tpau_2178 | Tpau_1702 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.936 |
| Tpau_2178 | cobD | Tpau_2178 | Tpau_2715 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.919 |
| Tpau_2178 | cobQ | Tpau_2178 | Tpau_1693 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.922 |
| Tpau_2178 | cobT | Tpau_2178 | Tpau_1527 | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.905 |
| Tpau_2179 | Tpau_2178 | Tpau_2179 | Tpau_2178 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; KEGG: msm:MSMEG_3878 precorrin-6Y C5,15- methyltransferase (decarboxylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.998 |
| Tpau_2179 | Tpau_2180 | Tpau_2179 | Tpau_2180 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6x reductase; KEGG: nfa:nfa31540 precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.996 |
| Tpau_2179 | Tpau_2190 | Tpau_2179 | Tpau_2190 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | precorrin-3B C17-methyltransferase; KEGG: rer:RER_31440 precorrin-2 C(20)- methyltransferase/precorrin-3B C(17)-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.999 |
| Tpau_2179 | Tpau_2191 | Tpau_2179 | Tpau_2191 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: nfa:nfa31510 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH. | 0.980 |
| Tpau_2179 | Tpau_2196 | Tpau_2179 | Tpau_2196 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: cobaltochelatase, CobN subunit; KEGG: rha:RHA1_ro00171 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase. | 0.837 |
| Tpau_2179 | Tpau_3353 | Tpau_2179 | Tpau_3353 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6A synthase (deacetylating); KEGG: cai:Caci_6988 precorrin-6A synthase (deacetylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.989 |
| Tpau_2179 | cobB-3 | Tpau_2179 | Tpau_1702 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.906 |
| Tpau_2179 | cobD | Tpau_2179 | Tpau_2715 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.852 |
| Tpau_2179 | cobQ | Tpau_2179 | Tpau_1693 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.971 |
| Tpau_2179 | cobT | Tpau_2179 | Tpau_1527 | TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: fra:Francci3_1523 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.942 |